http://medeponyms.com/feed/ Keep track of the articles added to MedEponyms.com http://medeponyms.com/entry/57/ Fri, 7 Oct 2011 10:40:00 -0500 http://medeponyms.com/entry/57/ Pinkus tumor (fibroepithelioma of Pinkus) is a variant of basal cell carcinoma characterized by arborizing strands of basaloid epithelium, two to three cells thick, that originate from the epidermis, extend downwards into the underlying dermis and anastomose with each other, dividing the stroma into compartments. http://medeponyms.com/entry/56/ Thu, 6 Oct 2011 10:24:00 -0500 http://medeponyms.com/entry/56/ Laugier-Hunziker syndrome (idiopathic lenticular mucocutaneous pigmentation) is a sporadic condition manifesting as benign melanotic macules on the oral mucosa and longitudinal pygmentation of the nails (longitudinal melanonychia). There is no systemic manifestations or increased risk of malignancy. http://medeponyms.com/entry/55/ Tue, 4 Oct 2011 08:45:00 -0500 http://medeponyms.com/entry/55/ Spongiform pustules of Kogoj are collection of neutrophils in the stratum spinosum seen in the skin lesions of patients with psoriasis. http://medeponyms.com/entry/54/ Tue, 4 Oct 2011 08:38:00 -0500 http://medeponyms.com/entry/54/ Munro microabscesses are collection of neutrophils in the parakeratotic stratum corneum seen in the skin lesions of patients with psoriasis. http://medeponyms.com/entry/53/ Mon, 3 Oct 2011 09:13:00 -0500 http://medeponyms.com/entry/53/ Zeis glands are modified sebaceous glands at the rim of the eylid. Unlike Meibomian glands, they are associated with hair follicles, and open into the infundibula of the eyelashes. http://medeponyms.com/entry/52/ Mon, 3 Oct 2011 09:07:00 -0500 http://medeponyms.com/entry/52/ Moll glands are modified apocrine sweat glands at the rim of the eyelid. http://medeponyms.com/entry/50/ Mon, 3 Oct 2011 09:06:00 -0500 http://medeponyms.com/entry/50/ Meibomian glands are modified sebaceous glands at the rim of the eylid. Unlike Zeis glands, they are not associated with hair follicles and open directly onto the skin surface. http://medeponyms.com/entry/51/ Mon, 3 Oct 2011 08:34:00 -0500 http://medeponyms.com/entry/51/ Tyson glands are modified sebaceous glands at the corona and the inner surface of the prepuce of the penis. http://medeponyms.com/entry/49/ Mon, 3 Oct 2011 07:27:00 -0500 http://medeponyms.com/entry/49/ Fordyce spots are ectopic sebaceous glands found on the mucosal surface of the lips, as well as genital skin of the scrotum, shaft of the penis and labia. Unlike normal sebaceous glands, they are not associated with hair follicles. Fordyce spots have no clinical significance and are of cosmetic concern only. http://medeponyms.com/entry/48/ Mon, 3 Oct 2011 07:21:00 -0500 http://medeponyms.com/entry/48/ Montgomery tubercles are sebaceous glands of the areola. http://medeponyms.com/entry/47/ Wed, 21 Sep 2011 05:34:05 -0500 http://medeponyms.com/entry/47/ Langhans giant cells is one of the three main subtypes of multinucleated giant cells (the other two being Touton giant cells and foreign body type giant cells). Histogenetically, all three types of giant cells are transformed macrophages. Morphologically, Langhans cells appear as multinucleated giant cells with a peripherally located ring of nuclei surrounding centrally located eosinophilic cytoplasm. Langhans giant cells are seen in mycobacterial and fungal infections, sarcoidosis and other conditions. http://medeponyms.com/entry/46/ Wed, 21 Sep 2011 05:30:13 -0500 http://medeponyms.com/entry/46/ Touton giant cells is one of the three main subtypes of multinucleated giant cells (the other two being Langhans giant cells and foreign body type giant cells). Histogenetically, all three types of giant cells are transformed macrophages. Morphologically, Touton cells appear as multinucleated giant cells with a ring of nuclei sepatating peripheral clear rim of cytoplasm from central, more eosinophilic cytoplasm. The peripheral cytoplasm appears clear due to high lipid content. Touton giant cells are seen in lesions with high lipid content, such as xanthoma, xanthogranuloma and fat necrosis. http://medeponyms.com/entry/45/ Wed, 21 Sep 2011 04:53:52 -0500 http://medeponyms.com/entry/45/ Feigin tumor is the eponym for gliosarcoma, an agressive glioma exhibiting biphasic glial and mesenchymal differentiation.Feigin tumor corresponds histologically to World Health Organization (WHO) grade IV. http://medeponyms.com/entry/44/ Tue, 31 May 2011 07:55:00 -0500 http://medeponyms.com/entry/44/ Carney triad is a rare non-hereditary syndrome characterized by the association of three tumors: gastrointestinal stromal tumor (GIST), pulmonary chondroma and extra-adrenal paraganglioma. http://medeponyms.com/entry/38/ Tue, 31 May 2011 07:54:00 -0500 http://medeponyms.com/entry/38/ Langerhans cells are bone marrow derived specialized antigen presenting dendritic cells that reside in the skin and mucosal membranes. Upon encountering an antigen, Langerhans cells become activated and then migrate via lymphatics to the regional lymph node, where they present the antigen to T cells. http://medeponyms.com/entry/43/ Tue, 31 May 2011 07:52:15 -0500 http://medeponyms.com/entry/43/ Langerhans cell sarcoma is an aggressive high-grade neoplasm of a Langerhans cell lineage. The neoplastic cells exhibit malignant cytologic features (hyperchromatic nuclei, prominent nucleoli, high mitotic rate). Immunophenotyping and/or ultrastructural studies are required to identify the Langerhans cell derivation. http://medeponyms.com/entry/42/ Tue, 31 May 2011 07:52:00 -0500 http://medeponyms.com/entry/42/ Hashimoto-Pritzker syndrome (Hashimoto-Pritzker congenital self-healing reticulohistiocytosis) is a rare form of Langerhans cell histiocytosis that is usually present at birth or develops in the early neonatal period. It manifests with multiple skin lesions over the head, trunk, palms and soles. The condition usually resolves spontaneously within weeks to months. In rare cases it may progress to a disseminated form (Letterer-Siwe disease). http://medeponyms.com/entry/41/ Tue, 31 May 2011 07:49:15 -0500 http://medeponyms.com/entry/41/ Letterer-Siwe disease is a disseminated form of Langerhans cell histiocytosis. It can occur at any age but is most common during the first year of life. Patients present with fever, cytopenias, hepatosplenomegaly, skin and bone lesions. http://medeponyms.com/entry/40/ Tue, 31 May 2011 07:49:00 -0500 http://medeponyms.com/entry/40/ Hand-Schüller-Christian disease is the multi-site form of Langerhans cell histiocytosis typically seen in young children. The classic presentation is that of osteolytic skull lesions, hypopituitarism with diabetes insipidus, and exophthalmos. Skin lesions are seen in one third of the cases. http://medeponyms.com/entry/39/ Tue, 31 May 2011 07:47:00 -0500 http://medeponyms.com/entry/39/ Langerhans cell histiocytosis is a clonal proliferation of a Langerhans cell lineage. The neoplastic cells express CD1a, S100 and langerin, and contain Birbeck granules in the cytoplasm by electron microscopy. http://medeponyms.com/entry/37/ Tue, 31 May 2011 07:42:00 -0500 http://medeponyms.com/entry/37/ Birbeck granule is a tennis racquet shaped organelle present in Langerhans cells. It is 200 to 400 nm long and 33 nm wide with a zipper like appearance. Birbeck granules are a hallmark of Langerhans cells. http://medeponyms.com/entry/36/ Fri, 15 Apr 2011 11:17:00 -0500 http://medeponyms.com/entry/36/ Clark nevus is a melanocytic nevus which shows architectural atypia. The atypical architectural features include asymmetry, irregular peripheral border of the lesion, shoulder phenomenon (extension of the junctional component of a compound nevus beyond its dermal component), lentiginous growth of solitary melanocytes along and focally in between elongated rete ridges, and bridging of junctional melanocytic nests. http://medeponyms.com/entry/35/ Thu, 14 Apr 2011 18:30:00 -0500 http://medeponyms.com/entry/35/ Miescher nevus is a subtype of ordinary, or common, melanocytic nevus. They are benign melanocytic proliferations which most commonly occur on the face and present as firm, tan to brown dome-shaped papules. http://medeponyms.com/entry/34/ Thu, 14 Apr 2011 21:16:00 -0500 http://medeponyms.com/entry/34/ Unna nevus is a subtype of ordinary, or common, melanocytic nevus. They are benign melanocytic proliferations which most commonly present as soft papillomatous lesions of the trunk, neck and extremities. http://medeponyms.com/entry/33/ Thu, 10 Mar 2011 10:20:00 -0500 http://medeponyms.com/entry/33/ Codman triangle is a subperiosteal area of newly formed reactive bone that develops due to the lifting of the periosteum by an aggressive bone lesion. It can be seen in neoplastic conditions (osteosarcoma, Ewing sarcoma, chondrosarcoma) as well as in infectious processes (osteomyelitis, subperiosteal abscess). http://medeponyms.com/entry/32/ Fri, 25 Feb 2011 09:25:00 -0500 http://medeponyms.com/entry/32/ Schmorl picrothionin stain is a histochemical stain for compact bone that is precipitation based. The staining reagent is composed of thionin and picric acid. Thionin precipitates in bone lacunae, canaliculi and cells, staining them blue to blue-black. Picric acid forms picrates in the bone matrix, staining it yellow. http://medeponyms.com/entry/31/ Fri, 25 Feb 2011 09:22:00 -0500 http://medeponyms.com/entry/31/ Schmorl reduction stain (Schmorl ferric-ferricyanide reduction stain, often referred to as Schmorl stain) is a histochemical stain based on reduction of ferricyanide to ferrocyanide, which is in turn converted to insoluble Prussian blue in the presense of ferric ions. http://medeponyms.com/entry/30/ Fri, 25 Feb 2011 08:37:00 -0500 http://medeponyms.com/entry/30/ Schmorl node is an upward or downward herniation of the intervertebral disc through the vertebral endplate into the adjacent vertebra. http://medeponyms.com/entry/29/ Fri, 25 Feb 2011 08:32:00 -0500 http://medeponyms.com/entry/29/ Fontana-Masson stain is a silver based histochemical stain. It is used for two purposes: (1) to demonstrate melanin and (2) to demonstrate argentaffin granules in neuroendocrine cells. The principle of the stain lies in reduction of silver nitrate to metallic silver which appears black. http://medeponyms.com/entry/28/ Wed, 09 Feb 2011 12:02:00 -0500 http://medeponyms.com/entry/28/ Kimmelstiel-Wilson syndrome (Kimmelstein-Wilson disease, diabetic nephropathy, nodular diabetic glomerulosclerosis) is a progressive glomerular angiopathy seen in patients with diabetes mellitus. It manifests as nephrotic syndrome, hypertension, and ultimately results in renal failure. Histologically, the kidneys exhibit various degrees of dlomerulosclerosis, with sclerotic glomeruli containing brightly eosinophilic Kimmelstein-Wilson nodules. http://medeponyms.com/entry/27/ Wed, 02 Feb 2011 21:02:00 -0500 http://medeponyms.com/entry/27/ Creola bodies are clumps of benign ciliated respiratory epithelium. They can be seen in spontaneously expectorated sputum of asthmatic patients, as well as in cytology preparations of bronchoalveolar lavage specimens. http://medeponyms.com/entry/26/ Thu, 27 Jan 2011 10:34:00 -0500 http://medeponyms.com/entry/26/ Sweet syndrome, also known as acute febrile neutrophilic dermatosis, most commonly involves skin of head, neck and upper extremities. It presents as tender, raised, erythematous, sharply demarcated plaques and papules, and is accompanied by systemic signs of fever and malaise. The neutrophil counts are elevated. The syndrome is often associated with systemic conditions (malignancy, inflammatory bowel disease) or medications. http://medeponyms.com/entry/25/ Thu, 13 Jan 2011 07:53:00 -0500 http://medeponyms.com/entry/25/ Lyell syndrome is a severe reactive dermatitis also known as toxic epidermal necrolysis (TEN). It is traditionally described in the erythema multiforme group of dermatitides. The group includes the continuum of erythema multiforme, Stevens-Johnson syndrome, and Lyell syndrome/TEN. http://medeponyms.com/entry/24/ Thu, 13 Jan 2011 07:52:00 -0500 http://medeponyms.com/entry/24/ Stevens-Johnson syndrome is a severe reactive dermatitis. It is traditionally described in the erythema multiforme group of dermatitides. The group includes the continuum of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis (TEN, also known as Lyell syndrome). http://medeponyms.com/ Tue, 30 Nov 2010 12:00:00 -0500 http://medeponyms.com/ The site has been completely redesigned. A whole new section of pathology review questions is coming soon.