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Azzopardi effect

Azzopardi effect is a histomorphogic phenomenon of incrustation of blood vessel wall with basophilic nuclear material. It hd been primarily described in small cell (neuroendocrine) carcinoma of the lung, but is non-specific and can be seen in other malignancies with a rapid cell turnover. On hematoxylin and eosin (H&E) stained sections blood vessels within or close to the tumor exhibit deeply basophilic staining of the full thickness of the wall.


Last updated: May 24, 2012, 3:35 pm EST

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